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李昺之

作者: 时间:2021-11-23 点击数:

姓名: 李昺之        

联系方式:bingzhili@njnu.edu.cn

电子邮箱:bingzhili@njnu.edu.cn

通信地址:南京师范大学学林路2号食品与制药工程学院

教育背景:

2010.9-2014.6,南京医科大学,药学,理学学士

2014.9-2019.6,南京医科大学,药物分析学,医学博士

主要研究方向:

药物分析学;化学计量学;合成生物学

主要社会兼职:

中国生物工程学会会员,Analytical ChemistryAnalytica Chimica ActaSensors and Actuators B-ChemicalFrontiers in Chemistry等期刊审稿人。

荣誉和获奖情况:

1. 中国粮油学会科学技术奖(二等奖),7/10,中国粮油学会,2020.10

2. 江苏省医学科技奖(二等奖),4/8,江苏省医学会,2020.12

3. 江苏省教育教学与研究成果奖(三等奖),5/5,江苏省教育厅,2018.08

近期发表论文(*通讯作者)

1. B. Li*, A. Xia, S. Xie, L. Lin, Z. Ji, T. Suo, X. Zhang*, H. Huang*, Signal-Amplified Detection of the Tumor Biomarker FEN1 Based on Cleavage-Induced Ligation of a Dumbbell DNA Probe and Rolling Circle Amplification. Anal. Chem. 2021, 93, 3287-3294.

2. B. Li, L. Xu, Y. Chen, W. Zhu, X. Shen, C. Zhu, J. Luo, X. Li, J. Hong, X. Zhou*, Sensitive and Label-Free Fluorescent Detection of Transcription Factors Based on DNA-Ag Nanoclusters Molecular Beacons and Exonuclease III-Assisted Signal Amplification. Anal. Chem. 2017, 89, 7316-7323.

3. B. Li, A. Xia, S. Zhang, T. Suo, Y. Ma, H. Huang*, X. Zhang*, Y. Chen*, X. Zhou*, A CRISPR-derived biosensor for the sensitive detection of transcription factors based on the target-induced inhibition of Cas12a activation. Biosens. Bioelectron. 2021, 173, 112619.

4. B. Li*, S. Xie, A. Xia, T. Suo, H. Huang*, X. Zhang*, Y. Chen*, X. Zhou, Recent advance in the sensing of biomarker transcription factors. TrAC Trend. Anal. Chem. 2020, 132, 116039.

5. B. Li*, T. Suo, S. Xie, A. Xia, Y. Ma, H. Huang, X. Zhang*, Q. Hu, Rational design, synthesis, and applications of carbon dots@metal–organic frameworks (CD@MOF) based sensors. TrAC Trend. Anal. Chem. 2021, 135, 116163.

6. B. Li#,*, P. Zhang#, B. Zhou, S. Xie, A. Xia, T. Suo, S. Feng*, X. Zhang*, Fluorometric detection of cancer marker FEN1 based on double-flapped dumbbell DNA nanoprobe functionalized with silver nanoclusters. Anal. Chim. Acta 2021, 1148, 238194.

7. B. Li, Z. Shao, Y. Chen*, An exonuclease protection and CRISPR/Cas12a integrated biosensor for the turn-on detection of transcription factors in cancer cells. Anal. Chim. Acta 2021, 338478.

8. B. Zhou, L. Lin*, B. Li*, Exponential amplification reaction-based fluorescent sensor for the sensitive detection of tumor biomarker flap endonuclease 1. Sensor. Actuat. B-Chem. 2021, 346, 130457.

9. T. Suo#, M. Sohail#, S. Xie, B. Li*, Y. Chen*, L. Zhang*, X. Zhang*, DNA nanotechnology: A recent advancement in the monitoring of microcystin-LR. J. Hazard. Mater. 2021, 403, 123418.

10. Y. Ji#, Z. Wu#, P. Zhang, M. Qiao, Y. Hu, B. Shen, B. Li*, X. Zhang*, Enzyme-functionalized magnetic framework composite fabricated by one-pot encapsulation of lipase and Fe3O4 nanoparticle into metal-organic framework. Biochem. Eng. J. 2021, 107962.

11. S. Xie, Z. Ji, T. Suo, B. Li*, X. Zhang*, Advancing sensing technology with CRISPR: from the detection of nucleic acids to a broad range of analytes – A Review. Anal. Chim. Acta 2021, 338848.

12. M. Qiao#, L. Zhang#, R. Jiao, S. Zhang, B. Li*, X. Zhang*, Chemical and enzymatic synthesis of S-linked sugars and glycoconjugates. Tetrahedron 2021, 131920.

13. Z. Ji#, Y. Ji#, R. Ding, L. Lin, B. Li*, X. Zhang*, DNA-templated silver nanoclusters as an efficient catalyst for reduction of nitrobenzene derivatives: a systematic study. Nanotechnology 2021, 32, 195705.

14. M. Qiao#, R. Jiao#, X. Zhang, Z. Wu, B. Shen*, B. Li*, 1H NMR analysis of perdeutero N-sulfoheparosan C5-epimerization: a direct way to measure the activity of immobilized C5-epimerase. J. Carbohyd. Chem. 2021, 1-13.

15. L. Lin#, B. Li#, X. Han, F. Zhang, X. Zhang*, R. J. Linhardt*, A rolling circle amplification based platform for ultrasensitive detection of heparin. Analyst 2021, 146, 714-720.

16. Y. Chen#, X. Yan#, W. Yang, J. Wang, Q. Lu, B. Li*, W. Zhu*, X. Zhou*, A signal transduction approach for multiplexed detection of transcription factors by integrating DNA nanotechnology, multi-channeled isothermal amplification, and chromatography. J. Chromatogr. A 2020, 1624, 461148.

17. T. Suo#, M. Sohail#, Y. Ma, B. Li*, Y. Chen*, X. Zhang*, X. Zhou*, A versatile turn-on fluorometric biosensing profile based on split aptamers-involved assembly of nanocluster beacon sandwich. Sensor. Actuat. B-Chem. 2020, 324, 128586.

18. B. Li, Y. Chen, J. Wang, Q. Lu, W. Zhu, J. Luo, J. Hong, X. Zhou, Detecting transcription factors with allosteric DNA-Silver nanocluster switches. Anal. Chim. Acta 2019, 1048, 168-177.

19. B. Li, Y. Chen, J. Wang, Q. Lu, W. Zhu, L. Xu, X. Shen, J. Luo, C. Zhu, X. Li, J. Hong, X. Zhou, DNA-silver nanoclusters/polypyrrole nanoparticles: A label-free and enzyme-free platform for multiplexed transcription factors detection. Sensor. Actuat. B-Chem. 2018, 274, 481-490.


南京师范大学食品与制药工程学院 ,南京市栖霞区学林路2号 TEL/FAX:86-25-85898183