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黄和

作者: 时间:2019-08-13 点击数:


黄和,男,1974年生,教授、博士生导师,获国家自然科学基金杰出青年基金项目资助,入选教育部长江学者奖励计划特聘教授、首批万人计划以及国家百千万人才工程1997年浙江大学生物化工专业本科毕业,2002年美国普渡大学化学工程专业博士毕业,现任南京师范大学食品与制药工程学院院长,兼任江苏省十三届人大常委会委员、全国青联委员、江苏省青联委员、中国化工学会理事、中国生物工程学会理事、亚洲生物技术协会(AFOB)执行委员会委员、中国化工学会生物化工专业委员会青年工作委员会执行主任等。

科研工作以微生物为核心,基于代谢工程,对微生物资源进行挖掘和分析,结合发酵工程等手段进行下游产品(生物基化学品、营养化学品、医药中间体等)的开发。研究成果获国家技术发明奖二等奖2项(2013年、2018年,排名1;教育部高等学校科学研究优秀成果奖技术发明一等奖2项(2017年、2012年,排名1)、中国轻工业联合会科学技术发明奖一等奖1项(2017年,排名1)、中国石油和化学工业联合会技术发明一等奖2项(2011年、2010年,分别排名12);获闵恩泽能源化工杰出贡献奖、比尔及梅琳达盖茨基金会青年科学家奖、AIChE(美国化学工程师协会)PLENARY AWARD。获得全国优秀科技工作者、全国化工优秀科技工作者、霍英东教育基金会第十二届高等院校青年教师奖、江苏青年五四奖章、国务院政府特殊津贴、国务院国家特聘专家等荣誉。

作为项目负责人承担国家自然科学基金杰出青年基金、国家自然科学基金重点基金、863重点项目、973项目子课题、中国石化科学技术研究开发项目等多项课题。授权发明专利72项,以通讯作者在Biotechnology Advances, ACS Catalysis, Green Chemistry等本领域权威期刊上发表SCI论文135篇,论文被SCI他引4036次,2014-2018年连续五年入选Elsevier化学工程领域中国高被引学者榜单。近年来代表成果如下:

1.      Ling Jiang, Xiaogang Song, Yingfeng Li, Qing Xu, Jiahua Pu, He Huang*, Chao Zhong*. Programming integrative extracellular and intracellular biocatalysis for rapid, robust and recyclable synthesis of trehalose. ACS Catalysis. 2018, 8: 1837−1842.

2.      Yin FW, Guo DS, Ren LJ*, Ji XJ, Huang H*. Development of a method for the valorization of fermentation wastewater and algal-residue extract in docosahexaenoic acid production by Schizochytrium sp. Bioresource Technol, 2018, 266: 482-487

3.      Sun XM, Ren LJ*, Bi ZQ, Ji XJ, Zhao QY, Jiang L, Huang H*. Development of a cooperative two-factor adaptive evolution method to enhance lipid production and prevent lipid peroxidation in Schizochytrium sp. Biotechnology for Biofuels  2018,11:65-80

4.      Ji XJ*, Huang H*. Engineering Microbes to Produce Polyunsaturated Fatty Acids. Trends in Biotechnology. 2018, DOI: 10.1016/j.tibtech.2018.10.002

5.      Ren LJ, Sun XM, Ji XJ, Chen SL, Guo DS, Huang H*. Enhancement of docosahexaenoic acid synthesis by manipulation of antioxidant capacity and prevention of oxidative damage in Schizochytrium sp. Bioresource Technol 2017, 223:141-148

6.      Liu HH, Ji XJ*, Huang H*. Biotechnological applications of Yarrowia lipolytica: Past, present and future. Biotechnology Advances. 2015;33:1522-1546.

7.      Jiang L, Cui HY, Zhu LY, Hu Y, Xu X, Li S, Huang H*. Enhanced propionic acid production from whey lactose with immobilized Propionibacterium acidipropionici and role of trehalose synthesis in acid tolerance. Green Chem. 2015. 17(1):250-259.

8.      Ji XJ*, Liu LG, Shen MQ, Nie ZK, Tong YJ, Huang H*. Constructing a synthetic metabolic pathway in Escherichia coli to produce the enantiomerically pure (R, R)-2,3-butanediol. Biotechnol Bioeng. 2015. 112(5):1056-1059

9.      Ren LJ, Zhuang XY, Chen SL, Ji XJ, Huang H*. Introduction of omega-3 desaturase obviously changed the fatty acid profile and sterol content of Schizochytrium sp. J Agr Food Chem. 2015. 63(44):9770-9776

10.  Ji XiaoJun*, Zhang Aihui, Nie Zhikui, Wu Wenjia, Ren Lujing, Huang He*. Efficient arachidonic acid-rich oil production by Mortierella alpina through a repeated fed-batch fermentation strategy. Bioresource Technology. 2014, 170: 356-360

11.  Ji Xiaojun, Ren Lujing, Nie Zhikui, Huang He*, Ouyang Pingkai. Fungal arachidonic acid-rich oil: research, development and industrialization. Critical Reviews Biotechnology. 2014, 34(3): 197-214.

12.  Xu Qing, Li Shuang, Huang He*, Wen Jianping. Key Technologies for the Industrial Production of Fumaric Acid by Fermentation. Biotechnology Advances. 2012, 30: 1685-1696

13.  Ji Xiaojun, Huang He*, Ouyang Pingkai. Microbial 2,3-Butanediol Production: A State-of-the-Art Review. Biotechnology Advances. 2011, 29: 351-364

14.  Ren Lujing, Sun Guannan, Ji Xiaojun, Hu Xuechao, Huang He*. Compositional shift in lipid fractions during lipid accumulation and turnover in Schizochytrium sp. Bioresource Technology. 2014, 157: 107-113.

15.  Gu Shuai, Xu Qing, Huang He*, Li Shuang*. Alternative respiration and fumaric acid production of Rhizopus oryzae. Applied Microbiology and Biotechnology. 2014, 98(11): 5145-5152

16.  Ji Xiaojun, Xia Zhifang, Fu Ninghua, Nie Zhikui, Shen Mengqiu, Tian Qianqian, Huang He*. Cofactor Engineering through Heterologous Expression of an Nadh Oxidase and Its Impact on Metabolic Flux Redistribution in Klebsiella Pneumoniae. Biotechnology for Biofuels. 2013, 6.

17.  Deng Yuefang, Li Shuang, Xu Qing, Gao Min, Huang He*. Production of Fumaric Acid by Simultaneous Saccharification Fermentation of Starchy Materials with 2-Deoxyglucose-Resistant Mutant Strains of Rhizopus Oryzae, Bioresource Technology. 2012, 107: 363-367

18.  Zheng Hongli, Gao Zhen, Yin Fengwei, Ji Xiaojun, Huang He*. Lipid Production of Chlorella Vulgaris from Lipid-Extracted Microalgal Biomass Residues through Two-Step Enzymatic Hydrolysis. Bioresource Technology. 2012, 117: 1-6.

19.  Jin Pin, Li Shuang, Lu Shengguo, Zhu Jianguo, Huang He*. Improved 1,3-Propanediol Production with Hemicellulosic Hydrolysates (Corn Straw) as Cosubstrate: Impact of Degradation Products on Klebsiella Pneumoniae Growth 1,3-Propanediol Fermentation. Bioresource Technology. 2011, 102: 1815-1821

20.  Xu Qing, Li Shuang, Fu Yongqian, Tai Chao, Huang He*. Two-Stage Utilization of Corn Straw by Rhizopus Oryzae for Fumaric Acid Production. Bioresource Technology. 2010, 101: 6262-6264.

 

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